Study Shows Possible Link Between Paxil and Suicidal Behavior

By Elizabeth Rhein

Published on August 23, 2005

The antidepressant Paxil, also known as paroxetine, was previously shown to increase the possibility of severe depression and suicide attempts when administered to children and teenagers. These findings resulted in the Food and Drug Administration's requirement of a "black box" warning on Paxil packaging, warning physicians of the possible danger.

Now, new studies from scientists at Oslo University point to similar behavior in adult Paxil patients. In the study, seven suicides were recorded in a group of 1500 people taking Paxil; among the control group, only one suicide was reported.

GlaxoSmithKline strongly disputes the study's validity, noting that data is 15 years old and selectively misleading. The drugmaker also points to other studies that show that the benefits of Paxil far outweigh any risk, especially when taken as directed under the care of a physician.

The Norwegian scientists conclude that governmental warnings regarding the effects of Paxil in children should be extended to include adults as well.

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