YAZ/Yasmin Contraceptive Risk Includes Drug Interactions
By Jim Greene
Published on February 15, 2010
Label warnings for the oral contraceptives YAZ® and Yasmin® include the possibility of adverse drug interactions, in addition to the possible direct side effects, primarily dangerous blood clots, that are the subject of numerous personal injury lawsuits. The two main drug interaction concerns are reduced contraceptive action and elevated potassium levels.
YAZ® is a newer variant of Yasmin®. Both are products of Bayer Health Care Pharmaceuticals. The company currently promotes only YAZ® in the United States, although litigation against Bayer includes both products.
Range of Drugs Threatens Reduced Contraception
The drugs that, when taken in combination with YAZ®/Yasmin®, reduce the contraceptive's effectiveness include barbiturates, certain seizure medications, the antibiotics Rifadin® (rifampin) and Minocin® (minocycline), protease inhibitors used to treat or prevent infection by HIV, hepatitis C, and other viruses; Provigil® (modafinil), used to treat narcolepsy, and the herbal supplement St. John's wort.
Elevated levels of potassium can cause hyperkalemia, a condition that can lead to a disruption of normal heart rhythm, possibly resulting in cardiac arrest. Drugs that may elevate potassium levels when taken in combination with YAZ®/Yasmin® include nonsteroidal anti-Inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, and naproxen; potassium supplements and potassium-sparing diuretics; and the blood thinner heparin.
Contraceptive May Increase Side Effects of Other Drugs
YAZ®/Yasmin® can also increase the likelihood of side effects associated with certain other drugs, when taken in combination with those drugs. These include cyclosporine, selegiline, all sold under various brand names.
There are several other possible drug interactions with YAZ®/Yasmin®. The safest course of action is to consult a physician or pharmacist for specific details.
If you or someone you know has suffered adverse drug interaction associated with YAZ®, such as heart issues related to hyperkalemia, other problems associated with elevated potassium levels, or injury or death caused by blood clots, contact an experienced product liability/personal injury attorney. You may be eligible to receive financial compensation for medical bills, loss of income, and other expenses that can threaten your financial future.
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